Analytical Contract Lab Providing Particle Size and Characterization Testing Services

(630) 969-2703

PTL Announces Paperless Reporting

Particle Technology Labs is pleased to announce that starting in early April, all final reports will be delivered to our clients digitally using Sharefile®, a file sharing service that securely transfers encrypted documents through an easy to use online portal.
 
How paperless reporting works.
 
When your final report is complete, you will receive an email with a link to Sharefile®  where you can log in to view your report instantly. If it is your first time using Sharefile®, you will need to sign up for an account, which is very simple. Just enter your name, company name and email. Once you are signed in, you can download your final report as a PDF document.
 
Final reports will remain available for download on Sharefile® for thirty days.
 
Further instructions for using Sharefile® are available by clicking here.

Multiple benefits. 

 
PTL is excited to deliver reports faster with a more positive environmental impact, while at the same time continuing to provide outstanding service and particle characterization results to our clients.

Visit PTL at the 8th World Congress on Particle Technology April 23rd – April 25, 2018

Particle Technology Labs invites you to join us April 23rd through the 25th, 2018 at the Orlando World Center Marriott in Orlando, Florida for the 8th World Congress on Particle Technology.

Held every 4 years since its inception in 1990, the WCPT8 is intended to stimulate discussions on the forefront of research in particle science and technology.
 
As experts in the field of fine particle technology, we welcome the opportunity to meet with you and discuss questions related to particle size and characterization. Feel free to contact us before the conference to schedule a time to meet during the conference. 630.403.0099.
 
For more info on the World Congress on Particle Technology itself, please visit

Not Attending?

If you are unable to attend WCPT8, please reach out to us to discuss your particle size and characterization needs.

New at PTL - 3Flex Surface and Catalyst Characterization

New at PTL - 3Flex Surface and Catalyst Characterization

Particle Technology Labs is pleased to announce the installation of our newest advanced instrument, the Micromeritics 3Flex Surface Characterization Analyzer.

The 3Flex instrument is capable of high-performance chemisorption and physisorption (mesopore and micropore) analyses with superior accuracy, resolution, and data reduction.

PTL’s model, the Micromeritics 3Flex Chemi TCD, has wide-ranging capabilities for various chemisorption methods. This includes isothermal methods (static volumetric, and dynamic or pulse chemisorption) as well as temperature programmed methods (temperature-programmed reduction or TPR, temperature-programmed oxidation or TPO, and temperature-programmed desorption or TPD). Furthermore, our instrument can also utilize an organic vapor source as the probe molecules (e.g., pyridine, isopropyl amine, methanol, etc.) in addition to standard gases (e.g., ammonia, H2, CO, etc.) most commonly used in various chemisorption analyses.

Chemisorption measurements are important for surface characterization of catalysts used in several industries including oil and gas (e.g. petroleum refining, syngas conversions, biofuel production, fuel cells), petrochemicals, fine chemicals (e.g. hydrogen production, polymers and plastics production), environmental (e.g. automotive catalytic converters, green chemistry), and many others.

Chemisorption

Chemical adsorption, or chemisorption, is a process resulting from a chemical bond between adsorbate molecules and specific surface locations on a material, known as active sites. This interaction is much stronger than physical adsorption, or physisorption, which takes place on all surfaces if temperature and pressure conditions are favorable. Chemisorption only occurs on clean active sites and, unlike physisorption, ceases when the adsorbate can no longer make direct contact with the surface, making chemisorption a single layer process.

Chemisorption measurement techniques are useful for evaluating physical and chemical properties of materials that are critical for process / reaction performance. Primarily, chemisorption is used to evaluate the number of available active sites to increase the rate of, or catalyze, chemical reactions. Other properties can include the (reduction or oxidation) temperature at which catalysts become active, strength of specific types of active sites, or ability of materials to perform after reduction/oxidation cycles.

To read more about chemisorption, click here.

Methods
ASTM D3908
Analyses Offered

Chemisorption Tests:

  • Volumetric Chemisorption analysis
  • Dynamic or Pulse Chemisorption analysis
  • Pulse Chemisorption using liquid vapors

Temperature-Programmed Studies:

  • Temperature-Programmed Reduction (TPR)
  • Temperature-Programmed Desorption (TPD)
  • Temperature-Programmed Oxidation (TPO)

Other Chemisorption Experiments:

  • Heat of Desorption, first order Kinetics
  • Isosteric Heat of Adsorption

Particle Technology Labs’ Director of Analytical Services Gives Presentation in Amsterdam

Particle Technology Labs’ Executive Vice President and Director of Analytical Services William K. Kopesky just returned from the Netherlands where he was one of three presenters at The Center for Professional Advancement’s course entitled, Powders: Their Properties and Processing. The three-day event took place December 11th through December 13th, 2017, in Amsterdam.

The primary purpose of the course was to “review the various properties of powdered solids pertinent to the development and manufacture of the products of the pharmaceutical, cosmetic and allied industries.”  While the course was designed for those in product development, the event was attended by scientists, suppliers and technologists.

During the three day course, Mr. Kopesky presented on the following topics:

In his first session, Characterization of Powder Particle Size and Shape, Mr. Kopesky provided insight regarding particle size analysis, distributions and their presentation, and particle shape characterization.

In his second session, Characterization of Particle Surface and Pores, he covered surface area by BET and pore size distribution measurement by both gas physisorption and mercury porosimetry.

In his third and final session, Fine Particle Characterization, dynamic light scattering (photon correlation spectroscopy), zeta potential and flocculation/agglomeration were covered.

Joining PTL as a Particle Characterization Chemist in 2000, Mr. Kopesky became Laboratory Manager in 2002 before being named Managing Director in 2008 and Director of Analytical Services in 2012. His years at PTL have given him exposure to a tremendous variety of particle characterization topics, techniques, and projects spanning many industries including pharmaceutical, nutraceutical, environmental, industrial, and more. During his career with PTL, he has conducted presentations and training in the field of particle characterization, provided testimony for patent infringement cases, and has been involved with consulting services in addition to hands-on analytical work.

The Center for Professional Advancement – CfPA is the largest accredited technical training organization in the world offering technical training and continuing professional education courses to those in the Pharmaceutical, Biotechnology, Medical Device, Chemical Engineering and Cosmetics industries.

For further information about CfPA, click here

To learn more about Particle Technology Labs, click here

Evolution of Particle Characterization Instrumentation – Advancing Test Methods for Upgraded Instrumentation

by Rebecca Wolfrom

Over time, advancements in technology have led to changes in many aspects of our lives. These advancements include improvements to tried-and-true scientific instruments, including those in the science of particle characterization.

Academic research continues to hone theories, and in turn the theories are built into software codes, hardware configurations, and even CFR Part 11 compliance programming. This means the instruments used while establishing a test method may be superseded by a newer model. In some fields, this may have a minimal effect on test results. But in particle characterization, it can mean significant differences in sensitivity, detection range, sample handling, or other factors. Any of these could mean a change in result relative to your specification – and no one likes surprises when it comes to meeting a specification.

This is where Particle Technology Labs comes in. At PTL, we’ve used particle characterization instrumentation all day, every day, for over 25 years. This translates to a high level of familiarity with the different techniques, theories, and upgraded equipment models. We stay up-to-date with the latest offerings from the manufacturers and are here to help with applying your method to the ever-evolving instrumentation.

Manufacturers can make a multitude of changes to their hardware in a single model upgrade. Such changes can include extended detection ranges, reconfigured flow paths, increased sensitivity, modified data capture rates, and automated sequences, to name just a few. While these features are often marketed as user-friendly benefits, they can present challenges when a body of work has already been established using a prior model. Some of the most interesting projects at PTL are those where the chemists investigate the effects of the new settings on the results and experiment until the puzzle is solved.

To meet the challenge presented by new instrument models, PTL first conducts internal studies to establish statistical equivalency between the legacy and new instrument model using reference materials. Each resulting report is available upon request to clients who are evaluating the need to make a move. Since the equivalency is demonstrated using model materials only, it is important to evaluate the results specific to the client’s own material. To do so, we first perform exploratory work to experimentally translate instrument settings from legacy to new model, and then we can add replicate testing to build confidence in the new method before it becomes routinely used. The scope of work is customizable to fit the client’s requirements.

PTL typically offers three levels of instrument model related method upgrades to choose from, at three different cost structures:

• A protocol-driven method transfer with repeat testing includes preliminary evaluation of the existing legacy method on the new instrument model, replicate analyses using the new method, statistical evaluation of the results with a comparison to historic method results if available, a copy of the new method, and a protocol and report both formally edited and approved by the client and PTL. The scope of the package is adjustable according to client need.

• A non-protocol-driven method change with repeat testing would include all of the above, but in place of the collaboratively reviewed protocol and report the client receives a PTL-generated standard report of analysis.

• A non-protocol-driven method change would include one analysis using the new instrument method based on PTL SOPs and scientific judgement and a PTL-generated standard report of analysis.

In all cases, the new method aims to maintain the same sample preparation procedures as employed in the legacy method (unless justified and approved by the client), but it adapts instrument settings as appropriate for the new hardware. If the legacy instrument is available at PTL, side-by-side analyses on both instrument models may be performed. Throughout the method change process, PTL standard operating procedures for both instrument operation and method revisions are upheld.

Do keep in mind that if a manufacturer has developed a new instrument model, it will only be a matter of time before the legacy model is removed from their maintenance and support plans. As such, PTL too will have to retire it. As a result, the original method cannot be sustained long-term. We make every effort to contact clients who are affected by these instrument retirements. We want to work with you to make the method change as smooth and scientifically supported as possible.

Contact Particle Technology Labs for more information.