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Particle Shape Factors and Their Use in Image Analysis – Part 1: Theory
ABSTRACT Fine particles are often characterized by their particle size and distribution as determined by various analytical instruments. Particle shape may be just as important as particle size. Particle shape, however, is often ignored or disregarded. Image analysis
The Importance of Sample Preparation When Measuring Specific Surface Area
ABSTRACT Specific surface area is a fundamental measurement in the field of fine particle characterization. Specific surface area measurements have numerous pharmaceutical manufacturing and quality applications. Compliance professionals should have a general understanding of the principles, procedures, and
Zeta Potential and Colloid Chemistry
ABSTRACT The US Food and Drug Administration often requests the measurement of zeta potential; however, there is virtually no guidance offered in any of the regulatory pharmacopoeias. Guidelines are available in other standards, and there exists a wealth
Particle Dispersion for Size Analysis
KEY POINTS The following key points are discussed: While particle size analysis can provide great insight in the pharmaceutical industry, it can be nearly meaningless if obtained improperly. A particle size distribution can be found for both colloidal
The Language of Particle Size
KEY POINTS The following key points are discussed: Knowledge and understanding of particle size data are vital to practitioners in the pharmaceutical, mining, environmental, paints and coatings, and other industries. The vocabulary of particle size is unique and
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Physical Measurement
What is the Difference Between Thermogravimetric Analysis (TGA) and Differential Scanning Calorimetry (DSC)
Spring is upon us, and with it comes fluctuating weather conditions! You’re enjoying some warmer days, but also a little worried how the extreme changes in temperature may affect your products. Thermal analysis can help you better understand
Pore Size
What Is Mercury Intrusion Porosimetry and When Is It Used?
You need to characterize the pore structure of your product, but you’re unsure of how best to do so. You’ve done your research and found a technique called Mercury Intrusion Porosimetry (MIP) but it’s unclear if this is
Particle Size
PTL now offering USP 788, USP 789 and USP 787 Testing
Particle Technology Labs is pleased to announce we are now offering USP <788> Particulate Matter in Injections testing, USP <789> Particulate Matter in Ophthalmic Solutions testing, and USP <787> Subvisible Particulate Matter in Therapeutic Protein Injections testing. Parenteral